Best Environmental Management Practice for the Waste Management Sector

The way communities generate and manage their waste plays an absolutely key role in their ability to use resources efficiently. While making European economy more resource efficient and circular requires a large spectrum of actions, a huge potential for saving resources lays in improving waste management at local level in Europe. On the basis of an in-depth analysis of the actions implemented by frontrunner organisations in the waste management sector, this report describes a set of best practices with high potential for broad uptake. They are called Best Environmental Management Practices (BEMPs) and aim to help local authorities in charge of waste management and waste management companies move towards circular economy. The BEMPs, identified in close cooperation with a technical working group comprising experts from the sector, cover the waste management areas which determine the most the overall waste management performance: setting a waste management strategy, promoting waste prevention, establishing an efficient waste collection that supports re-use and recycling, and stimulating waste and product re-use. Certain areas of waste treatment are also covered. The BEMPs address mainly the management of municipal solid waste, but also of construction and demolition waste and healthcare waste. Additionally, the report provides a set of environmental performance indicators that organisations can use to assess their waste management performance and monitor progress as well as benchmarks of excellence that give an indication of the levels achieved by best performers. The report presents a wide range of information (environmental benefits, economics, case studies, references, etc.) for each of the best practices and aims to provide inspiration and guidance to organisations of the sector. In addition, the report will be the technical basis for the development of an EMAS (EU Eco-Management and Audit Scheme) Sectoral Reference Document on Best Environmental Management Practice for the Waste Management sector according to Article 46 of Regulation (EC) No 1221/2009 (EMAS Regulation).JRC.B.5-Circular Economy and Industrial Leadershi

Best Environmental Management Practice for the Car Manufacturing Sector Learning from frontrunners

The European automotive industry is one of the EU's largest manufacturing sectors, and the automotive value chain covers many activities largely carried out within the EU, such as design and engineering, manufacturing, maintenance and repair, and end-of-life vehicle (ELV) handling. This Best Practice report describes Best Environmental Management Practices (BEMPs), i.e. techniques, measures or actions that are implemented by the organisations within the sector which are most advanced in terms of environmental performance in areas such as energy and resource efficiency, emissions, or supply chain management. The BEMPs provide inspirational examples for any organisation within the sector to improve its environmental performance. The report firstly outlines technical information on the contribution of car manufacturing and end-of-life vehicle (ELV) handling to key environmental burdens in the EU, alongside data on the economic relevance of the sector. The second chapter presents best environmental management practice of interest primarily for manufacturing companies (car manufacturers and associated manufacturers in the supply chain) covering cross-cutting issues related to key environmental impacts (such as energy, waste, water management, or biodiversity) before exploring best practice linked to specific topics, such as supply chain management. Subsequently, specific information concerning actors in the treatment of end-of-life vehicles is presented in the third chapter, focussing in particular on best practice applicable to processers of ELVs. This Best Practice Report was developed with support from a Technical Working Group of experts from the car manufacturing and ELV sector and associated fields. The report gives a wide range of information (environmental benefits, economics, indicators, benchmarks, references, etc.) for each of the proposed best practices in order to be a source of inspiration and guidance for any company of the sector wishing to improve environmental performance. In addition, it will be the technical basis for a Sectoral Reference Document on the car manufacturing sector, to be produced by the European Commission according to the EMAS Regulation.JRC.B.5-Circular Economy and Industrial Leadershi

Best Environmental Management Practice in the Fabricated Metal Product manufacturing sector

This report encloses technical information pertinent to the development of Best Environmental Management Practices (BEMPs) for the Sectoral Reference Document on the Fabricated Metal Products manufacturing sector, to be produced by the European Commission according to Article 46 of Regulation (EC) No 1221/2009 (EMAS Regulation). The BEMPs, both of technological and management nature (identified in close cooperation with a technical working group) address all the relevant environmental aspects of the Fabricated Metal Products manufacturing facilities. The BEMPs described in this report provide guidance on the cross-cutting issues and optimisation of utilities of the manufacturing facilities. Moreover, the BEMPs cover also the most relevant manufacturing processes, looking at energy and material efficiency, protecting and enhancing biodiversity, using of renewable energy and using rationally and effectively chemicals e.g. for cooling of various machining processes. Each BEMP gives a wide range of information and outlines the achieved environmental benefits, appropriate environmental performance indicators to measure environmental performance against the proposed benchmarks of excellence, economics etc. aiming at giving inspiration and guidance to any company of the sector who wishes to improve its environmental performance.JRC.B.5-Circular Economy and Industrial Leadershi

Best Environmental Management Practice for the Food and Beverage Manufacturing Sector

This report describes best environmental management practices for food and beverage manufacturers. Best environmental management practices are those techniques, measures and actions that can be implemented by food and beverage manufacturers to minimise their impact on the environment all along the value chain of their products. They were identified together with sectoral experts on the basis of practices actually implemented by environmental frontrunners. The report outlines best environmental management practices that are broadly applicable to all food and beverage manufacturers, such as the carrying out of an environmental assessment, sustainable supply chain management, cleaning operations, improvement of energy efficiency, use of renewable energy, optimisation of transport and distribution, refrigeration and freezing operations and food waste prevention. Additionally, specific best practices for nine individual subsectors are presented, namely the processing of coffee, manufacture of olive oil, manufacture of soft drinks, manufacture of beer, production of meat and poultry meat products, manufacture of fruit juice, cheese making operations, manufacture of bread, biscuits and cakes and manufacture of wine. Alongside best environmental management practices, the report also identifies suitable sector specific environmental performance indicators related to the topic of each best practices, and, when possible, benchmarks of excellence, corresponding to the level of performance achieved by frontrunners. This report can be used by food and beverage manufacturers as a source of information to identify relevant actions they can implement to improve their environmental performance. On its basis, the EMAS (EU Eco-Management and Audit Scheme) Sectoral Reference Document on Best Environmental Management Practice for the food and beverage manufacturing sector was developed (according to Article 46 of Regulation (EC) No 1221/2009).JRC.B.5-Circular Economy and Industrial Leadershi

Best Environmental Management Practice in the Telecommunications and ICT Services sector: Learning from front runners

The steady growth over the past decades of the Telecommunications and ICT Services sector, and its uninterrupted progress with the constant provision of renewed and ever-faster services as well as new applications, has transformed many aspects of our society and lives but has also spurred the development of ever more power- and resource-hungry systems, contributing to the sector’s ever-growing environmental footprint. On the basis of an in-depth analysis of the actions implemented by environmental front runners and of existing EU and industry initiatives addressing the environmental performance of the sector, this report describes a set of best practices with high potential for larger uptake. These are called Best Environmental Management Practices (BEMPs). The BEMPs, identified in close cooperation with a technical working group comprising experts from the sector, cover improvement of environmental performance across all significant environmental aspects (energy consumption, resource consumption, etc.) at the different life cycle stages (planning and design, installation, operation, end-of-life management, etc.) and for different ICT assets (software, data centres, etc.). Besides actions aimed at reducing the environmental impact of Telecommunications and ICT Services operations (with a special focus on data centres and telecommunications networks), the report also identifies best practices in the ICT sector that contribute towards reducing the environmental impact of other sectors of the economy ("greening by ICT" measures). The report gives a wide range of information (environmental benefits, economics, indicators, benchmarks, references, etc.) for each of the proposed best practices in order to be a source of inspiration and guidance for any company in the sector wishing to improve its environmental performance. In addition, it will be the technical basis for a Sectoral Reference Document on Best Environmental Management Practice for the Telecommunications and ICT Services sector, to be produced by the European Commission according to Article 46 of Regulation (EC) No 1221/2009 (EMAS Regulation).JRC.B.5-Circular Economy and Industrial Leadershi

Stakeholder needs analysis towards a new concept for the identification and promotion of Best Environmental Management Practices

The European Commission has been identifying and promoting Best Environmental Management Practices (BEMPs) in implementation of a provision of the (EU) Eco-Management and Audit Scheme (EMAS) Regulation. BEMPs are those actions or techniques resulting in improvements of environmental performance well above common practice that can be implemented by organisations in different sectors. They are identified by the European Commission's Joint Research Centre (JRC) working in close cooperation with sectoral technical working groups (TWG) on the basis of the actions implemented by frontrunner organisations. They are used, on a voluntary basis, by both EMAS registered organisations and all other organisations interested in improving their environmental performance. This stakeholder need analysis was performed to identify the major improvement opportunities in the development and promotion of BEMPs, by taking into account the main needs and barriers faced by stakeholders, with the goal to develop and validate possible solutions to a future format and approach. On these basis, this stakeholder need analysis provides information on the main barriers and needs faced by organisations in the improvement of environmental performance and identifies an interactive web-tool with sectoral specific content and features as the recommended format and approach for both developing and promoting BEMPs, as well as continuing to make available a report with detailed information about the best environmental practices.JRC.B.5-Circular Economy and Industrial Leadershi

High Data Output and Automated 3D Correlative Light–Electron Microscopy Method

Correlative light/electron microscopy (CLEM) allows the simultaneous observation of a given subcellular structure by fluorescence light microscopy (FLM) and electron microscopy. The use of this approach is becoming increasingly frequent in cell biology. In this study, we report on a new high data output CLEM method based on the use of cryosections. We successfully applied the method to analyze the structure of rough and smooth Russell bodies used as model systems. The major advantages of our method are (i) the possibility to correlate several hundreds of events at the same time, (ii) the possibility to perform three-dimensional (3D) correlation, (iii) the possibility to immunolabel both endogenous and recombinantly expressed proteins at the same time and (iv) the possibility to combine the high data analysis capability of FLM with the high precision–accuracy of transmission electron microscopy in a CLEM hybrid morphometry analysis. We have identified and optimized critical steps in sample preparation, defined routines for sample analysis and retracing of regions of interest, developed software for semi/fully automatic 3D reconstruction and defined preliminary conditions for an hybrid light/electron microscopy morphometry approach

Bridging therapeutic opportunities: a survey by the Italian molecular tumor board workgroup of Alliance Against Cancer

Background: Molecular tumor boards (MTBs) match molecular alterations with targeted anticancer drugs upon failure of the available therapeutic options. Special and local needs are most likely to emerge through the comparative analysis of MTB networks, but these are rarely reported. This manuscript summarizes the state-of-art of 16 active Italian MTBs, as it emerges from an online survey curated by Alliance Against Cancer (ACC).Main text: Most MTBs (13/16) are exclusively supported through local Institutional grants and meet regularly. All but one adopts a fully virtual or a mixed face-to-face/virtual calling/attendance meeting model. It appears that the ACC MTB initiative is shaping a hub-and-spoke virtual MTB network reminiscent of non-redundant, cost-effective health-care organization models. Unfortunately, public awareness of MTB opportunities presently remains insufficient. Only one center has a website. Dedicated e-mail addresses are for the exclusive use of the MTB staff. More than half of ACC members consider a miscellanea of most or all solid and hematological malignancies, and more than one-third consider neoplasms arising at any anatomical location. The average number of Staff Members in MTBs is 9. More than 10 staff members simultaneously attend MTB meetings in 13 MTBs. A medical oncologist is invariably present and is in charge of introducing the clinical case either with (45%) or without previous discussion in organ-specific multidisciplinary Boards. All but two MTBs take charge of not only patients with no standard-of-care (SoC) therapy option, but also cases receiving NGS profiling in SoC settings, implying a larger number of yearly cases. All MTBs run targeted NGS panels. Three run whole-exome and/or RNAseq approaches. ESCAT-ESMO and/or Onco-KB levels of evidence are similarly used for diagnostic reporting. Most MTBs (11) provide a written diagnostic report within 15 days. Conclusions are invariably communicated to the patient by the medical oncologist.Conclusions: MTB networking is crucial not only for molecular diagnosis and therapy assignment, but also for healthcare governance. Survey results show that MTBs review therapeutic opportunities at the crossover between standard-of-care with off-label, the former task being much beyond their scope. Societal and scientific implications of this beyond-the-scope MTB function may be relevant for healthcare in Italy and abroad

Anxiety and depression in keratotic oral lichen planus: a multicentric study from the SIPMO

Objectives: Oral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated with a complex symptomatology and psychological alteration. The aim of the study was to evaluate the prevalence of anxiety (A) and depression (D) in patients with K-OLP, analyzing the potential predictors which can affect mental health status. Methods: Three hundred K-OLP patients versus 300 healthy controls (HC) were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), and Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A) were administered. Results: The K-OLP patients showed statistically higher scores in the NRS, T-PRI, HAM-D, and HAM-A compared with the HC (p-value < 0.001**). A and D were found in 158 (52.7%) and 148 (49.3%) K-OLP patients. Strong linear correlations were identified between HAM-A, HAM-D, NRS, T-PRI, and employment status and between HAM-D, HAM-A, NRS, T-PRI, employment status, and female gender. Multivariate logistic regression revealed that HAM-D and HAM-A showed the greatest increase in the R2 value for A and D in the K-OLP patients, respectively (DR2 = 55.5% p-value < 0.001**; DR2 = 56.5% p-value < 0.001**). Conclusions: The prevalence of A and D is higher in the K-OLP patients compared with the HC, also found in K-OLP subjects without pain, suggesting that the processing of pain may be in a certain way independent of the processing of mood. Clinical relevance: Mood disorders and pain assessment should be carefully performed in relation to K-OLP to obtain a complete analysis of the patients